BioGears
BioGears is an open source, comprehensive, extensible human physiology engine released under the Apache 2.0 license that will drive medical education, research, and training technologies. BioGears enables accurate and consistent physiology simulation across the medical community. The engine can be used as a standalone application or integrated with simulators, sensor interfaces, and models of all fidelities.
Download NowWhat Can BioGears Do?
Several features set BioGears above the rest:
- BioGears includes mathematical models for a wide range of systems, medical interfaces, and substances for real-time retrieval of accurate physiology state.
- The common data model includes standard inputs, outputs, units, conversions, and naming conventions that make model additions and product integration quick and easy.
- Our website is a place for discussion and sharing among our community of users. Explore showcase scenarios, collaborate with us on GitHub, and use the tutorials to guide BioGears integration.
- A full-featured API, SDK, code-based documentation, and tutorial examples make BioGears easy to understand and use. Rigorous validation methods ensure accurate model output.
Community Focused
BioGearsEngine.com includes all the documentation you will need to use and modify BioGears. We support and engage our community of users through GitHub, Twitter, conferences and access to code-based documentation. We hope you can visit us at one of our upcoming events!
Work With Us!
Applied Research Associates, Inc. (ARA) is the company developing the BioGears open source physiology engine and we are always looking for research partners and sponsors! The BioGears team is interested in talking to you about extensions and applications of BioGears, and new biomedical engineering projects.
Below, we provide downloadable information, presentations about BioGears, and our contact information.
We look forward to working together!
Explore a Scenario Explore More Scenarios
Soldier Multi-Trauma
The Soldier Multi-Trauma Showcase Scenario simulates the injuries that a Combat Medic or other caregiver may encounter on the battlefield. This scenario highlights the ability of the BioGears physiology engine to simulate multiple insults occurring simultaneously. We have incorporated a tension pneumothorax with a massive hemorrhage. The tension pneumothorax is itself a combinatory insult, affecting both the respiratory and cardiovascular systems. Combining the tension pneumothorax with the blood loss from the hemorrhage pushes and eventually exceeds the limits of the homeostatic control mechanisms.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Environment Exposure
The Environment Exposure Showcase Scenario simulates the physiology of an adult woman who is exposed to cold weather long enough to develop hypothermia. This scenario highlights the ability of the BioGears physiology engine to simulate physiology when the body is exposed to an abnormal environment.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Asthma Attack
The Asthma Attack Showcase Scenario simulates physiology during an asthma attack and after administration of a beta-agonist. This scenario highlights the ability of the BioGears physiology engine to simulate asthma and inhaled-drug administration.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Heat Stroke
The heat stroke scenario simulates the body's temperature regulation system. This scenario highlights the ability of the BioGears physiology engine to simulate the energy exchange between the human body and the environment.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Sepsis
The sepsis scenario highlights the biogears inflammation/infection model and subsequent treatments. Patient reactions were validated with the University of Washington Advanced Modular Manikin project. During the onset of severe septic infection originating in the gut the patient sees symptoms in line with SIRS: increased core temperature, elevated white blood cell count and an elevated respiration rate. Treatments in line with best practice patient management. BioGears supports antibiotics, fluid infusions, and norepinephrine administration.
Scenario Timeline
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Whats Next?
Easy! Get started with your new BioGears project, take a look at the documentation, and interact with our growing community over at GitHub.
