- General bug fixes and updates
- Finalization for testing and implementation to BioGears override functionality with full physiology request data support
- Arterial and Venous PH data requests
- Inflammation state data to support sepsis model serialization
- Generalized sepsis model to a more generic inflammation model
- Will be critical to future modeling efforts (hemorrhage, burn, infection)
- New example sepsis xml files (SepsisSevere_Gut.xml
- New lymph circuit
- Handles Albumin transport and re-circulation
- Creates realistic oncotic pressure sources for substance transport
- Transport from tissue systems back into the vasculature via lymph
- New command line utility project (cmd_bio) for native c++ runtime, driver, batch run organizer/manager
- Optional name value for xml actions meal and environment
- New burn model
- User defined total body surface area input
- Inflammation cascade validated for long running scenarios (24 hr+)
- Validated for traditional treatment protocols with USISR SMEs
- New unit testing framework (Google Test) to better support multiplatform functionality
- Unit Test harness is a separate project in CMAKE which can be controlled with Biogears_BUILD_TEST variable
- Introduced const char* DLL interfaces for all functions dealing with std::string to avoid windows related issues dealing with XSD implicitly exporting string through inheritance
- Updated functionality to tension pneumothorax to fix bug in bilateral behavior
- Updated hemorrhage bugs to update blood gas levels in metabolic requirements
- Validated with University of Washington
- Patches to drug blood pressure modifications to restrict pathways to be more physiologically accurate
- Vasopressin support and validation
- Major patches to #include requirements, reduction in file dependencies
- Increased modularity of the project, increased build times during development
- Change in how we generate code from our CDM XSD files to one file per XSD file instead of per type
- Reduced build times for the full source from 40 to 10 min
- Empty constructors in SETypes to = default and adding override markers
- No longer use stdafx.h while compiling, and many headers make direct reference to CommonDataModel.h and Biogears.h, which were previously bundled in these precompiled headers
- Override functionality now supported in BioGears
- May override any physiology data request with desired value
- Logging will document range of possible values if typing unsupported data
- Engine can now be globally flagged as conformant or non conformant to increase future development possibilities
- Can be manipulated via action api calls
- Example xmls and sdks demonstrate functionality
- Moved all BioGears functionality in to the BioGears namespace
- BioGears python plotting tool
- Max work rate now a patient parameter and is configurable
- Hemorrhage action updates, may now specify location and rate
- Rate will diminish as pressure in the vessel decreases
- Update build process to be entirely supported by CMAKE
- Removed Apache Ant dependency
- Updated build directory and runtime directory dependencies
- Full build support for arm platforms
- Updates to source to support all major platforms: mac, win, linux, and Arm
- Updated build architecture to python buildbot libraries
- 8 concurrent nightly builds to ensure multi-platform support
- Setup mirroring onto our new github repository
- All development now open to the community with feature branches also supporting nightly builds
- Dockerfile and testing/support now supported, see more at https://cloud.docker.com/u/biogears/repository/docker/biogears/engine
- Pain model and patient pain susceptibility configuration flag
- Validated pain model supported, stimulus can be specified with severity from 0-1
- Works with all supported pain medication in the BioGears engine
- Treat patient with Morphine, Fentanyl, and/or Ketamine
- New How-to-pain file to display sdk support
- Sepsis model
- Robust whole body inflammation model with severity and location specifiers in .xml and SDK
- New How-to-sepsis file to show sdk functionality (command-line tool)
- Validated treatments with fluid resuscitation guidelines, vasopressin, norepinephrine, and antibiotics
- Validated blood chemistry markers such as bilirubin, white blood cell count, and lactate
- New antibiotic IV drip
- Can be used to treat sepsis
- Two new supported patients: toughguy and toughgirl
- Sweat rate patches now meeting validation
- Better core temperature regulation during exercise
- Hyper/hypo-hidrosis now a supported patient parameter
- Updates and new 7.0 java GUI release to support users who want to create their own substance
- Includes ability to patch in new drugs
- Chemoreceptor method updated to track validation for hypercapnic and hypoxic conditions
- Better support for respiratory validation across the board, particularly supported respiratory conditions
- Patches to saline infusion loading on the patient for better respiratory validation
